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Filtered Search Results
Medchemexpress LLC 1,3-Dimethoxybenzene | 151-10-0 | 99.99% | 138.17 | 25 MG
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1,3-Dimethoxybenzene is a volatile compound with sweet medicinal, hazelnut, resinous, and woody notes. It has been identified as a new volatile component in grape musts and port wines from the Douro region. This product is intended for research use only.
- Volatile compound with distinct aromas
- Found in grape musts and port wines
- Liquid appearance, colorless to light yellow
- Ships at room temperature (continental US)
- Pure form storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Solubility in DMSO: ≥ 100 mg/mL
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eMolecules 13588-28-8 | 2-(2-Methoxypropoxy)propan-1-ol | MFCD19707082 | 100mg
Medchem Express | OSMI-1 | 5mg | 599150495 | HY-119738 | 1681056-61-0 | MFCD30187585 | 563.640 | C28H25N3O6S2
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Medchemexpress LLC NVP-AST 487 | 630124-46-8 | 98.9% | 529.56 | 100 MG
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AST 487 (NVP-AST 487) is a potent RET kinase inhibitor and also inhibits Flt-3, KDR, c-Kit, and c-Abl kinases. It demonstrates strong inhibitory effects on the growth of human thyroid cancer cell lines with activating RET mutations and mutant FLT3 inhibitor activity, making it suitable for various research applications in cancer and other related disease areas.
- Inhibits RET kinase with an IC50 of 880 nM
- Inhibits Flt-3 with an IC50 of 520 nM
- Potently inhibits growth of human thyroid cancer cell lines with activating RET mutations
- Novel, mutant FLT3 inhibitor
- Inhibits KDR, c-Kit, and c-Abl kinase
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Medchemexpress LLC Tcmdc-135051 hydrochloride | 2705545-47-5 | 98.2% | 508.05 | C29H34ClN3O3 | 100MG
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TCMDC-135051 hydrochloride is the hydrochloride salt of TCMDC-135051, a selective and potent inhibitor of Plasmodium falciparum cyclin-dependent-like kinase 3 (PfCLK3) intended for research use in biochemical and cellular studies.
- selective PfCLK3 inhibition with low off-target toxicity.
- high purity suitable for research applications.
- light yellow to yellow solid form for easy handling.
- stable when stored sealed and protected from moisture.
- provided in small quantities for assay development and screening.
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Medchemexpress LLC HY-103015 1mg Medchemexpress, WZ4141 CAS:1222776-76-2 Purity:>98%
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Medchemexpress, HY-103015 1mg WZ4141 CAS:1222776-76-2 WZ4141 is an API intermediate. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Diethylmaleate 141-05-9 100mg
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Diethylmaleate (141-05-9) is a small-molecule compound that depletes intracellular glutathione (GSH) modulating cellular redox-sensitive pathways Diethylmaleate exerts its biological activity primarily through induction of oxidative stress and ROS generation leading to modulation of cell cycle apoptosis gene expression and activation of MAPK signaling pathways In vitro studies demonstrate that Diethylmaleate-mediated GSH depletion triggers cell cycle arrest and apoptosis Animal research shows effects on reproductive systems including altered testicular antioxidant status and sperm parameters Based on these pharmacological properties Diethylmaleate holds research potential in studies of oxidative stress redox regulation and toxicology
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Medchemexpress LLC HY-10398 5mg Medchemexpress, CTS-1027 CAS:193022-04-7 Purity:>98%
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Medchemexpress, HY-10398 5mg CTS-1027 CAS:193022-04-7 CTS-1027 is a potent small molecule inhibitor of MMPs, with IC50s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-119039 10mg Medchemexpress, RU-301 CAS:1110873-99-8 Purity:>98%
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Medchemexpress, HY-119039 10mg RU-301 CAS:1110873-99-8 RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Aobchem AOBCHEM
5000944746 4 -PHENOXY- 1 1 -BIPHENYL -4-C
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eMolecules 19848-54-5 | 2-Hydrazino-3-methylpyrazine | Apollo Scientific | MFCD19201409 | 124.147 | C5H8N4 | 95.000 | Cc1nccnc1NN | 1g | 562446294
2-Hydrazino-3-methylpyrazine | Apollo Scientific | 19848-54-5 | MFCD19201409 | 124.147 | C5H8N4 | 95.000 | Cc1nccnc1NN | 1g | 562446294
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eMolecules 2018300-62-2 | Medchem Express | TPOP146 | 5mg | 446255908 | HY-100697 | MFCD31382131 | 481.593 | C27H35N3O5
Ambeed | 22-Difluoroacetamide | 5g | 600837617 | A326465 | 359-38-6 | MFCD01896431 | 95.049 | C2H3F2NO
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eMolecules 1013750-77-0 | Medchem Express | ML-030 | 5mg | 446257942 | HY-103050 | 412.46 | C20H20N4O4S
Ambeed | 2-(4455-Tetramethyl-132-dioxaborolan-2-yl)-9H-fluoren-9-one | 250mg | 696731920 | A334841 | 1021306-45-5 | MFCD16294551 | 306.170 | C19H19BO3
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eMolecules 63302-99-8 | Medchem Express | Azaphen (dihydrochloride monohydrate) | 100mg | 446271701 | HY-A0022A | MFCD00220368 | 388.29 | C16H23Cl2N5O2
Medchem Express | Azaphen (dihydrochloride monohydrate) | 100mg | 446271701 | HY-A0022A | 63302-99-8 | MFCD00220368 | 388.290 | C16H23Cl2N5O2
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![Medchemexpress LLC 2-Thiophenemethanamine, N-[(4-chloro-2-methylphenyl)methyl]-N-[(4-chlorophenyl)methyl]-5-nitro- (hydrochloride) | 98.5% | 457.80 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000436961-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-Thiophenemethanamine, N-[(4-chloro-2-methylphenyl)methyl]-N-[(4-chlorophenyl)methyl]-5-nitro- (hydrochloride) | 98.5% | 457.80 | 10 MG
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GSK2945 hydrochloride is a tertiary amine, and is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. GSK2945 hydrochloride enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism. It is intended for research use only and is not sold to patients.
- Highly specific Rev-erbα/REV-ERBα antagonist
- Enhances cholesterol 7α-hydroxylase (CYP7A1) level
- Promotes cholesterol metabolism
- Increases the transcriptional activity of Rev-erbα
- Upregulates Lrh-1/LRH-1 mRNA and protein
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Medchemexpress LLC GNE-371 | 1926986-36-8 | 98.1% | 431.49 | 10 MG
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GNE-371 is a potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like. It binds TAF1(2) with an IC50 of 10 nM, showing excellent selectivity over other bromodomain-family members. It is also active in a cellular TAF1(2) target-engagement assay (IC50=38 nM) and demonstrates anti-proliferative synergy with the BET inhibitor JQ1, supporting its use in mechanistic and target-validation studies.
- Potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like.
- IC50 of 10 nM for TAF1(2).
- Active in a cellular TAF1(2) target-engagement assay (IC50=38 nM).
- Exhibits anti-proliferative synergy with the BET inhibitor JQ1.
- Appearance: Solid, white to off-white.
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